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EARLY Access [Video] with Dr. David Fajgenbaum
🕑 Added 2025-09-28 18:21:43 +0000 UTCDr. David Fajgenbaum, MD, MBA, MSc, is a pioneering physician-scientist, tenured professor at the Perelman School of Medicine at the University of Pennsylvania, and national bestselling author who transformed his personal battle with the rare, deadly Castleman disease into a global mission to accelerate cures for humanity's 12,000 known diseases.
Diagnosed after losing his mother to cancer, Fajgenbaum endured five near-death experiences before using his medical training to identify sirolimus—a repurposed drug—as a life-saving treatment, achieving remission, marking over a decade cancer-free as of 2025.
A Georgetown University graduate with advanced degrees from Oxford and Wharton, he co-founded the Castleman Disease Collaborative Network (CDCN) and Every Cure, leveraging AI and drug repurposing to unlock hidden treatments, earning spots on TIME's 2025 TIME100 Health list and major media recognition for his "cure thyself" story. Through his book Chasing My Cure and speaking engagements, Fajgenbaum inspires hope, advocates for patient-driven research, and pushes for policy changes to speed up cures for rare diseases affecting millions worldwide.
![EARLY Access [Video] with Dr. David Fajgenbaum](https://img10.runfaps.com/storage/7/ms/ha/e9630c-019e8a43-6ae6-72b3-8d03-8e5857bbd349.jpg)
Comments
Marc
The very last minute of the show choked me up.
JIM NEWMAN
SRS………..why don’t you link books, donations etc in your store. Doesn’t need to be everyone, but many ,in my opinion, are deserving
Ronni Swort
Amazing. I'm always looking for legitimate organizations to donate to. This absolutely is one of the best. I'm wondering if he's done any research involving Lyme disease.
Adir Iakya
Wonderful! Thank you.
Jello
@ShawnRyan when are you gonna get Marcus Luttrell on the show? I’ve been saying for years that it would be an absolute amazing experience & journey!
Michael King
This episode hit so hard. I have lost most of my family to cancer and disease. When he said his mom’s last words were “unconditional love“ I fucking broke down. Thank you Shawn for bringing this man’s fight to us so that we can lift him and his charity up towards success. Thank you Dr. Fajgenbaum for your dedication and warrior spirit to fight for every life affected by disease.
Melissa
Even though I do not like technology sometimes, AI can be used in these cases because it could help people living with chronic illnesses by preventing them from progressing.
Steven Peters
Another incredible episode! The cancer drugs your guest was given are life saving. They do come back to bite you later in life. We know through experience. Again, another amazing person.
Tindog
Interview of hope. God put him thru hell to do what he does today. Much like Pyfer and many other guests on your show. I can see the golden thread that knits them together. It’s their struggle to survive.
Richard “Papa” Beemer
What a truly touching, outstanding, and informative interview. To think dad/we used DMSO on our roping and reining horses to massage tight muscles and ligaments and the cross reference of pharma research into other diseases is brilliant........I truly believe God has appointed Dr. Fajgenbaum for a time such as this, I will be donating as well to this worthy research team. SRS Team/Shawn keep up the great work!
Michael Brown
Another great show!!!
Michele McDermott
I just donated/ not as much as I’d like - I’m on a fixed income. I lost my husband to pancreatic cancer- he was 59. Pancreatic cancer is a death sentence. We tried everything- he never gave up💔
